recombinant human il- 1ra Search Results


il 1 beta receptor antagonist rhil 1ra  (R&D Systems)
94
R&D Systems il 1 beta receptor antagonist rhil 1ra
Il 1 Beta Receptor Antagonist Rhil 1ra, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/il 1 beta receptor antagonist rhil 1ra/product/R&D Systems
Average 94 stars, based on 1 article reviews
il 1 beta receptor antagonist rhil 1ra - by Bioz Stars, 2026-03
94/100 stars
  Buy from Supplier
il 1ra  (MedChemExpress)
93
MedChemExpress il 1ra
Behavioral phenotype of mice in each group. (A) Schematic representation of the experimental design. (B) Open field test representative trajectory graph. (C) Elevated plus-maze test representative trajectory graph. (D) Open field test results. (E) Elevated plus-maze test results. (F) Attack behavior test results. Data are expressed as means ± SEMs. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. Control, producers of non-aggressive behavior after stress; Model, aggressive behavior after stress; A804598, P2X7R antagonist; <t>IL-1Ra,</t> IL-1β blocker; NLRP3 −/− , NLRP3 knockout mice. n = 8/group. (TIFF format, 1200 dpi, 2-column fitting image).
Il 1ra, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/il 1ra/product/MedChemExpress
Average 93 stars, based on 1 article reviews
il 1ra - by Bioz Stars, 2026-03
93/100 stars
  Buy from Supplier
il 1ra protein  (R&D Systems)
94
R&D Systems il 1ra protein
Behavioral phenotype of mice in each group. (A) Schematic representation of the experimental design. (B) Open field test representative trajectory graph. (C) Elevated plus-maze test representative trajectory graph. (D) Open field test results. (E) Elevated plus-maze test results. (F) Attack behavior test results. Data are expressed as means ± SEMs. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. Control, producers of non-aggressive behavior after stress; Model, aggressive behavior after stress; A804598, P2X7R antagonist; <t>IL-1Ra,</t> IL-1β blocker; NLRP3 −/− , NLRP3 knockout mice. n = 8/group. (TIFF format, 1200 dpi, 2-column fitting image).
Il 1ra Protein, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/il 1ra protein/product/R&D Systems
Average 94 stars, based on 1 article reviews
il 1ra protein - by Bioz Stars, 2026-03
94/100 stars
  Buy from Supplier
il 1ra  (Boster Bio)
90
Boster Bio il 1ra
Behavioral phenotype of mice in each group. (A) Schematic representation of the experimental design. (B) Open field test representative trajectory graph. (C) Elevated plus-maze test representative trajectory graph. (D) Open field test results. (E) Elevated plus-maze test results. (F) Attack behavior test results. Data are expressed as means ± SEMs. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. Control, producers of non-aggressive behavior after stress; Model, aggressive behavior after stress; A804598, P2X7R antagonist; <t>IL-1Ra,</t> IL-1β blocker; NLRP3 −/− , NLRP3 knockout mice. n = 8/group. (TIFF format, 1200 dpi, 2-column fitting image).
Il 1ra, supplied by Boster Bio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/il 1ra/product/Boster Bio
Average 90 stars, based on 1 article reviews
il 1ra - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
il1ra  (R&D Systems)
93
R&D Systems il1ra
Behavioral phenotype of mice in each group. (A) Schematic representation of the experimental design. (B) Open field test representative trajectory graph. (C) Elevated plus-maze test representative trajectory graph. (D) Open field test results. (E) Elevated plus-maze test results. (F) Attack behavior test results. Data are expressed as means ± SEMs. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. Control, producers of non-aggressive behavior after stress; Model, aggressive behavior after stress; A804598, P2X7R antagonist; <t>IL-1Ra,</t> IL-1β blocker; NLRP3 −/− , NLRP3 knockout mice. n = 8/group. (TIFF format, 1200 dpi, 2-column fitting image).
Il1ra, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/il1ra/product/R&D Systems
Average 93 stars, based on 1 article reviews
il1ra - by Bioz Stars, 2026-03
93/100 stars
  Buy from Supplier
il 1 ra  (R&D Systems)
93
R&D Systems il 1 ra
(a) The plantar incision induced a reduction in mechanical threshold against von Frey stimulation. Intrathecal <t>IL-1RA</t> administration significantly inhibited the reduction of the mechanical threshold for 6 h after the treatment. (b) The plantar incision induced a reduction in latency time against thermal stimulation. Intrathecal IL-1RA administration significantly inhibited reduction in the thermal pain latency for 6 h after the treatment. Data were analyzed by repeated measures two-way ANOVA, with Bonferroni’s multiple comparison test comparing pre- and post-treatment time points for each group ( # p < .05, ## p < .01, ### p < .001), and Bonferroni’s multiple comparison test comparing both groups at each time point (* p < .05, ** p < .01, *** p < .001). The data in the graphs are presented as the mean ± SEM ( n = 6 in each group). i.t.: intrathecal administration. Intrathecal administration of IL-1β induced reduction of the mechanical threshold against von Frey stimulation (c) and reduction of latency time against thermal stimulation (d). Data were analyzed by repeated measures two-way ANOVA, with Bonferroni’s multiple comparison test comparing pre- and post-treatment time points for each group ( # p < .05, ## p < .01) and Bonferroni’s multiple comparison test comparing both groups at each time point (* p < .05, ** p < .01). The data in the graphs are presented as the mean ± SEM ( n = 6 in each group).
Il 1 Ra, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/il 1 ra/product/R&D Systems
Average 93 stars, based on 1 article reviews
il 1 ra - by Bioz Stars, 2026-03
93/100 stars
  Buy from Supplier
interleukin 1 receptor antagonist  (MedChemExpress)
93
MedChemExpress interleukin 1 receptor antagonist
(a) The plantar incision induced a reduction in mechanical threshold against von Frey stimulation. Intrathecal <t>IL-1RA</t> administration significantly inhibited the reduction of the mechanical threshold for 6 h after the treatment. (b) The plantar incision induced a reduction in latency time against thermal stimulation. Intrathecal IL-1RA administration significantly inhibited reduction in the thermal pain latency for 6 h after the treatment. Data were analyzed by repeated measures two-way ANOVA, with Bonferroni’s multiple comparison test comparing pre- and post-treatment time points for each group ( # p < .05, ## p < .01, ### p < .001), and Bonferroni’s multiple comparison test comparing both groups at each time point (* p < .05, ** p < .01, *** p < .001). The data in the graphs are presented as the mean ± SEM ( n = 6 in each group). i.t.: intrathecal administration. Intrathecal administration of IL-1β induced reduction of the mechanical threshold against von Frey stimulation (c) and reduction of latency time against thermal stimulation (d). Data were analyzed by repeated measures two-way ANOVA, with Bonferroni’s multiple comparison test comparing pre- and post-treatment time points for each group ( # p < .05, ## p < .01) and Bonferroni’s multiple comparison test comparing both groups at each time point (* p < .05, ** p < .01). The data in the graphs are presented as the mean ± SEM ( n = 6 in each group).
Interleukin 1 Receptor Antagonist, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/interleukin 1 receptor antagonist/product/MedChemExpress
Average 93 stars, based on 1 article reviews
interleukin 1 receptor antagonist - by Bioz Stars, 2026-03
93/100 stars
  Buy from Supplier
recombinant human il-1r antagonist (rhil-1ra)  (ImmunoTools)
90
ImmunoTools recombinant human il-1r antagonist (rhil-1ra)
(a) The plantar incision induced a reduction in mechanical threshold against von Frey stimulation. Intrathecal <t>IL-1RA</t> administration significantly inhibited the reduction of the mechanical threshold for 6 h after the treatment. (b) The plantar incision induced a reduction in latency time against thermal stimulation. Intrathecal IL-1RA administration significantly inhibited reduction in the thermal pain latency for 6 h after the treatment. Data were analyzed by repeated measures two-way ANOVA, with Bonferroni’s multiple comparison test comparing pre- and post-treatment time points for each group ( # p < .05, ## p < .01, ### p < .001), and Bonferroni’s multiple comparison test comparing both groups at each time point (* p < .05, ** p < .01, *** p < .001). The data in the graphs are presented as the mean ± SEM ( n = 6 in each group). i.t.: intrathecal administration. Intrathecal administration of IL-1β induced reduction of the mechanical threshold against von Frey stimulation (c) and reduction of latency time against thermal stimulation (d). Data were analyzed by repeated measures two-way ANOVA, with Bonferroni’s multiple comparison test comparing pre- and post-treatment time points for each group ( # p < .05, ## p < .01) and Bonferroni’s multiple comparison test comparing both groups at each time point (* p < .05, ** p < .01). The data in the graphs are presented as the mean ± SEM ( n = 6 in each group).
Recombinant Human Il 1r Antagonist (Rhil 1ra), supplied by ImmunoTools, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/recombinant human il-1r antagonist (rhil-1ra)/product/ImmunoTools
Average 90 stars, based on 1 article reviews
recombinant human il-1r antagonist (rhil-1ra) - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier

Image Search Results


Behavioral phenotype of mice in each group. (A) Schematic representation of the experimental design. (B) Open field test representative trajectory graph. (C) Elevated plus-maze test representative trajectory graph. (D) Open field test results. (E) Elevated plus-maze test results. (F) Attack behavior test results. Data are expressed as means ± SEMs. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. Control, producers of non-aggressive behavior after stress; Model, aggressive behavior after stress; A804598, P2X7R antagonist; IL-1Ra, IL-1β blocker; NLRP3 −/− , NLRP3 knockout mice. n = 8/group. (TIFF format, 1200 dpi, 2-column fitting image).

Journal: Frontiers in Pharmacology

Article Title: The NLRP3 inflammasome is involved in resident intruder paradigm-induced aggressive behaviors in mice

doi: 10.3389/fphar.2023.974905

Figure Lengend Snippet: Behavioral phenotype of mice in each group. (A) Schematic representation of the experimental design. (B) Open field test representative trajectory graph. (C) Elevated plus-maze test representative trajectory graph. (D) Open field test results. (E) Elevated plus-maze test results. (F) Attack behavior test results. Data are expressed as means ± SEMs. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. Control, producers of non-aggressive behavior after stress; Model, aggressive behavior after stress; A804598, P2X7R antagonist; IL-1Ra, IL-1β blocker; NLRP3 −/− , NLRP3 knockout mice. n = 8/group. (TIFF format, 1200 dpi, 2-column fitting image).

Article Snippet: Chemicals are listed as follows: A804598 (HY-100483, MedChemExpress Co., Ltd. United States); IL-1Ra (HY-P7029A, MCE, United States); DMSO (D8370, Solarbio, China); Mouse NLRP3 ELISA kit (JYM0765Mo, Wuhan ColorfulGene biological technology Co., Ltd. China); Mouse IL-1β ELISA kit (JYM0531Mo, Wuhan ColorfulGene biological technology Co., Ltd. China); BCA Protein Assay Kit (PC0020, Solarbio, China); SDS-PAGE Gel Rapid Preparation Kit (G2037-50T, Servicebio, China); Recombinant Anti-beta Actin antibody (GB15003, Servicebio, China); NLRP3 Antibody (DF7438, Affinity Biologicals, Canada); Recombinant Anti-P2X7 antibody (ab259942, abcam, United Kingdom); HRP-conjugated goat anti-rabbit IgG (GB23204, Servicebio, China); Anti-Iba1 Rabbit pAb (GB11105, Servicebio, China); Cy3-labeled goat anti-rabbit IgG (GB21303, Servicebio, China); FITC-labeled goat anti-rabbit IgG (GB22303, Servicebio, China); Anti-BrdU Mouse mAb (GB12051, Servicebio, China); Anti-NeuN Rabbit pAb (GB11138, Servicebio, China); HE staining solution (G1005-100ML, Servicebio, China).

Techniques: Control, Knock-Out

The P2X7R was activated in the resident intruder paradigm. (A) Representative images of P2X7R (green) and DAPI (blue) labeling in the hippocampus CA1, CA3, and DG after drug interventions; scale bar = 200 and 50 µm. (B) Positive staining area of P2X7R and DAPI double-labeled (P2X7R + DAPI) proteins in the hippocampus CA1 (** p < 0.01 Control vs. Model ; n = 3/group), CA3 (** p < 0.01 Control vs. Model ; * p < 0.05 A804598 vs. Model ; n = 3/group), and DG (** p < 0.01 Control vs. Model ; * p < 0.05 A804598 vs. Model ; n = 3/group). (C) Representative immunoreactive bands showing the protein levels of hippocampal P2X7R in the Control, Model, A804598, IL-1Ra, and NLRP3 −/− mice. (D) Statistical results show that A804598, IL-1Ra, and NLRP3 −/− decreased the protein expression of P2X7R ( n = 3, **** p < 0.0001 vs. Model).

Journal: Frontiers in Pharmacology

Article Title: The NLRP3 inflammasome is involved in resident intruder paradigm-induced aggressive behaviors in mice

doi: 10.3389/fphar.2023.974905

Figure Lengend Snippet: The P2X7R was activated in the resident intruder paradigm. (A) Representative images of P2X7R (green) and DAPI (blue) labeling in the hippocampus CA1, CA3, and DG after drug interventions; scale bar = 200 and 50 µm. (B) Positive staining area of P2X7R and DAPI double-labeled (P2X7R + DAPI) proteins in the hippocampus CA1 (** p < 0.01 Control vs. Model ; n = 3/group), CA3 (** p < 0.01 Control vs. Model ; * p < 0.05 A804598 vs. Model ; n = 3/group), and DG (** p < 0.01 Control vs. Model ; * p < 0.05 A804598 vs. Model ; n = 3/group). (C) Representative immunoreactive bands showing the protein levels of hippocampal P2X7R in the Control, Model, A804598, IL-1Ra, and NLRP3 −/− mice. (D) Statistical results show that A804598, IL-1Ra, and NLRP3 −/− decreased the protein expression of P2X7R ( n = 3, **** p < 0.0001 vs. Model).

Article Snippet: Chemicals are listed as follows: A804598 (HY-100483, MedChemExpress Co., Ltd. United States); IL-1Ra (HY-P7029A, MCE, United States); DMSO (D8370, Solarbio, China); Mouse NLRP3 ELISA kit (JYM0765Mo, Wuhan ColorfulGene biological technology Co., Ltd. China); Mouse IL-1β ELISA kit (JYM0531Mo, Wuhan ColorfulGene biological technology Co., Ltd. China); BCA Protein Assay Kit (PC0020, Solarbio, China); SDS-PAGE Gel Rapid Preparation Kit (G2037-50T, Servicebio, China); Recombinant Anti-beta Actin antibody (GB15003, Servicebio, China); NLRP3 Antibody (DF7438, Affinity Biologicals, Canada); Recombinant Anti-P2X7 antibody (ab259942, abcam, United Kingdom); HRP-conjugated goat anti-rabbit IgG (GB23204, Servicebio, China); Anti-Iba1 Rabbit pAb (GB11105, Servicebio, China); Cy3-labeled goat anti-rabbit IgG (GB21303, Servicebio, China); FITC-labeled goat anti-rabbit IgG (GB22303, Servicebio, China); Anti-BrdU Mouse mAb (GB12051, Servicebio, China); Anti-NeuN Rabbit pAb (GB11138, Servicebio, China); HE staining solution (G1005-100ML, Servicebio, China).

Techniques: Labeling, Staining, Control, Expressing

Correlations between the expression levels of NLRP3 in the hippocampus or serum and aggressive behaviors. (A) Representative immunoreactive bands showing the protein levels of hippocampal NLRP3 in the Control, Model, A804598, IL-1Ra, and NLRP3 −/− mice. (B) Statistical results show that A804598, IL-1Ra, and NLRP3 −/− decreased the protein expression of NLRP3 ( n = 3, **** p < 0.0001 vs. Model). (C) NLRP3 and IL-1βhippocampus and serum levels. (D) Pearson correlation analyses were performed by comparing the expression levels of NLRP3 in the hippocampus or serum and aggressive behavior latency or aggressive behavior score. Correlations were performed considering some animals ( N = 3). The coefficient r and p -value for each correlation are presented in a box. Statistically significant correlations are highlighted in red ( p < 0.05). Data are expressed as means ± SEMs. Control, producers of non-aggressive behavior after stress; Model, aggressive behavior after stress; A804598, P2X7R antagonist; IL-1Ra, IL-1β blocker; NLRP3 −/− , NLRP3 knockout mice. (TIFF format, 1200 dpi, 2-column fitting image).

Journal: Frontiers in Pharmacology

Article Title: The NLRP3 inflammasome is involved in resident intruder paradigm-induced aggressive behaviors in mice

doi: 10.3389/fphar.2023.974905

Figure Lengend Snippet: Correlations between the expression levels of NLRP3 in the hippocampus or serum and aggressive behaviors. (A) Representative immunoreactive bands showing the protein levels of hippocampal NLRP3 in the Control, Model, A804598, IL-1Ra, and NLRP3 −/− mice. (B) Statistical results show that A804598, IL-1Ra, and NLRP3 −/− decreased the protein expression of NLRP3 ( n = 3, **** p < 0.0001 vs. Model). (C) NLRP3 and IL-1βhippocampus and serum levels. (D) Pearson correlation analyses were performed by comparing the expression levels of NLRP3 in the hippocampus or serum and aggressive behavior latency or aggressive behavior score. Correlations were performed considering some animals ( N = 3). The coefficient r and p -value for each correlation are presented in a box. Statistically significant correlations are highlighted in red ( p < 0.05). Data are expressed as means ± SEMs. Control, producers of non-aggressive behavior after stress; Model, aggressive behavior after stress; A804598, P2X7R antagonist; IL-1Ra, IL-1β blocker; NLRP3 −/− , NLRP3 knockout mice. (TIFF format, 1200 dpi, 2-column fitting image).

Article Snippet: Chemicals are listed as follows: A804598 (HY-100483, MedChemExpress Co., Ltd. United States); IL-1Ra (HY-P7029A, MCE, United States); DMSO (D8370, Solarbio, China); Mouse NLRP3 ELISA kit (JYM0765Mo, Wuhan ColorfulGene biological technology Co., Ltd. China); Mouse IL-1β ELISA kit (JYM0531Mo, Wuhan ColorfulGene biological technology Co., Ltd. China); BCA Protein Assay Kit (PC0020, Solarbio, China); SDS-PAGE Gel Rapid Preparation Kit (G2037-50T, Servicebio, China); Recombinant Anti-beta Actin antibody (GB15003, Servicebio, China); NLRP3 Antibody (DF7438, Affinity Biologicals, Canada); Recombinant Anti-P2X7 antibody (ab259942, abcam, United Kingdom); HRP-conjugated goat anti-rabbit IgG (GB23204, Servicebio, China); Anti-Iba1 Rabbit pAb (GB11105, Servicebio, China); Cy3-labeled goat anti-rabbit IgG (GB21303, Servicebio, China); FITC-labeled goat anti-rabbit IgG (GB22303, Servicebio, China); Anti-BrdU Mouse mAb (GB12051, Servicebio, China); Anti-NeuN Rabbit pAb (GB11138, Servicebio, China); HE staining solution (G1005-100ML, Servicebio, China).

Techniques: Expressing, Control, Knock-Out

(a) The plantar incision induced a reduction in mechanical threshold against von Frey stimulation. Intrathecal IL-1RA administration significantly inhibited the reduction of the mechanical threshold for 6 h after the treatment. (b) The plantar incision induced a reduction in latency time against thermal stimulation. Intrathecal IL-1RA administration significantly inhibited reduction in the thermal pain latency for 6 h after the treatment. Data were analyzed by repeated measures two-way ANOVA, with Bonferroni’s multiple comparison test comparing pre- and post-treatment time points for each group ( # p < .05, ## p < .01, ### p < .001), and Bonferroni’s multiple comparison test comparing both groups at each time point (* p < .05, ** p < .01, *** p < .001). The data in the graphs are presented as the mean ± SEM ( n = 6 in each group). i.t.: intrathecal administration. Intrathecal administration of IL-1β induced reduction of the mechanical threshold against von Frey stimulation (c) and reduction of latency time against thermal stimulation (d). Data were analyzed by repeated measures two-way ANOVA, with Bonferroni’s multiple comparison test comparing pre- and post-treatment time points for each group ( # p < .05, ## p < .01) and Bonferroni’s multiple comparison test comparing both groups at each time point (* p < .05, ** p < .01). The data in the graphs are presented as the mean ± SEM ( n = 6 in each group).

Journal: Molecular Pain

Article Title: Rapid cleavage of IL-1β in DRG neurons produces tissue injury-induced pain hypersensitivity

doi: 10.1177/17448069241285357

Figure Lengend Snippet: (a) The plantar incision induced a reduction in mechanical threshold against von Frey stimulation. Intrathecal IL-1RA administration significantly inhibited the reduction of the mechanical threshold for 6 h after the treatment. (b) The plantar incision induced a reduction in latency time against thermal stimulation. Intrathecal IL-1RA administration significantly inhibited reduction in the thermal pain latency for 6 h after the treatment. Data were analyzed by repeated measures two-way ANOVA, with Bonferroni’s multiple comparison test comparing pre- and post-treatment time points for each group ( # p < .05, ## p < .01, ### p < .001), and Bonferroni’s multiple comparison test comparing both groups at each time point (* p < .05, ** p < .01, *** p < .001). The data in the graphs are presented as the mean ± SEM ( n = 6 in each group). i.t.: intrathecal administration. Intrathecal administration of IL-1β induced reduction of the mechanical threshold against von Frey stimulation (c) and reduction of latency time against thermal stimulation (d). Data were analyzed by repeated measures two-way ANOVA, with Bonferroni’s multiple comparison test comparing pre- and post-treatment time points for each group ( # p < .05, ## p < .01) and Bonferroni’s multiple comparison test comparing both groups at each time point (* p < .05, ** p < .01). The data in the graphs are presented as the mean ± SEM ( n = 6 in each group).

Article Snippet: Mice were randomly assigned to saline and IL-1 RA (500 ng/5 μL, diluted in saline, Recombinant Human IL-1ra/IL-1F3, #280-RA/CF, R&D Systems, Inc. Minneapolis, MN 55413) groups ( n = 6 per group).

Techniques: Comparison